منابع مشابه
Screening pneumococci for penicillin resistance.
Eighty-four pneumococci with various MICs of penicillin (38 with MICs of less than or equal to 0.06 micrograms/ml [susceptible], 35 with MICs of 0.12 to 1.0 micrograms/ml [relatively resistant], and 11 with MICs of greater than 1.0 micrograms/ml [resistant] ) were screened by a disk diffusion test using oxacillin and methicillin to see how well they distinguished penicillin-susceptible strains ...
متن کاملCarriage of penicillin resistant pneumococci.
A survey of 303 urban and 156 rural children showed nasopharyngeal carriage of relatively resistant Streptococcus pneumoniae organisms in 14.2% and 19.2% of children, respectively. These organisms have minimum inhibitory concentrations for penicillin in the range of 0.12-1 microgram/ml. An analysis of 40 relatively resistant S. pneumoniae strains showed resistance to co-trimoxazole in 47.5%, tr...
متن کاملA biological price of antibiotic resistance: major changes in the peptidoglycan structure of penicillin-resistant pneumococci.
Pneumococcal strains with greatly elevated levels of resistance to penicillin have by now been described with increasing frequency worldwide. The mechanism of antibiotic resistance in these strains involves the molecular remodeling of cell wall synthetic enzymes (penicillin binding proteins). We have now analyzed the peptidoglycan structures of 10 penicillin-susceptible and 10 penicillin-resist...
متن کاملQuinolone resistance mechanisms in pneumococci.
Quinolones are widely used in the treatment of respiratory infections, in large part because of their activity against Streptococcus pneumoniae and other commonly encountered respiratory tract pathogens. Pneumococcal isolates that are resistant to these "respiratory quinolones" have now begun to emerge. Resistance is attributable to mutations affecting the intracellular targets of these drugs, ...
متن کاملPhenotypes and genes of resistance of pneumococci to penicillin isolated from children.
UNLABELLED (Full text is available at http://www.manu.edu.mk/prilozi). In recent decades, the increase of Streptococcus pneumoniae strains resistant to beta-lactams, to other classes of antimicrobial drugs and especially to penicillin (penicillin-resistant pneumococcus - PRP) has further complicated the treatment of pneumococcal infection. Penicillin resistance in pneumococci is due to the deve...
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ژورنال
عنوان ژورنال: Journal of Antimicrobial Chemotherapy
سال: 2000
ISSN: 1460-2091
DOI: 10.1093/jac/45.5.710